Investigating two mysterious deaths in a small town, Sam and Dean discover a witch is sacrificing people to summon an ancient powerful and extremely dangerous demon.
Sam, Dean, and Ruby discover the existence of a female prophet named Anna Milton, who can hear the voices of angels and thus figures into the plans of a demon named Ala...
Dean and Sam figure out why Castiel and Uriel want Anna Milton dead when the three of them are forced to go on the run, not only from heavenly and vengeful angels, but ...
Castiel and Uriel ask Dean to torture Alastair for information. But when Alastair breaks free, Castiel starts to believe that there is a traitor among the angels.
In an alternate reality mysteriously created as if Sam and Dean were never brothers and have never met, Sam and Dean work at a marketing office where they are forced to...
Sam and Dean are contacted by one Adam Milligan who claims to be John Winchester's son. The boys immediately suspect a demon trap and go to investigate. Adam turns out ...
Castiel has been sent back to Heaven. His human host, Jimmy, tries to regain his life. But the demons won't leave him alone and now his family is at risk. Sam and Dean ...
Sam is becoming more and more inhuman. Dean and Bobby put him in the safe hold until he gets over his addictions. After Sam escapes with help, unknown to him, from Cast...